XT-8® Panels
GenMark Diagnostics is committed to meeting customer needs with a broad menu of multiplex molecular products. The products presented in this section are available only in the U.S. at this time.
Respiratory Viral Panel
GenMark’s Respiratory Viral Panel (RVP) provides sensitive and specific respiratory virus detection with an optimized workflow to maximize laboratory efficiency.
Comprehensive Testing
- Detects 14 of the most common respiratory viruses associated with respiratory illness
Clear, Accurate Results
- Single-page reports with easy-to-interpret results
- The most sensitive RVP test based on independent studies including 99.2% agreement with qPCR1,2
Simple Workflow
- Scalable workflow to meet peak demand
- Batch based testing supports high throughput laboratories
Respiratory Viral Panel Targets | |
Adenovirus B/E | Influenza A 2009 H1N1 |
Adenovirus C | Influenza B |
Human Metapneumovirus | Parainfluenza Virus 1 |
Human Rhinovirus | Parainfluenza Virus 2 |
Influenza A | Parainfluenza Virus 3 |
Influenza A H1 | Respiratory Syncytial Virus A |
Influenza A H3 | Respiratory Syncytial Virus B |
For in vitro diagnostic use
1. Pierce, V.M., Hodinka, R.L. (2012). Comparison of the GenMark Diagnostics eSensor Respiratory Viral Panel to Real-Time PCR for Detection of Respiratory Viruses in Children. Journal of Clinical Microbiology, 50(11), 3458-3465.
2. Popowitch, E.B. et al. An Analytical Comparison of Four Commercial Respiratory Virus Panels. Poster presented at 28th Annual Clinical Virology Symposium and Annual Meeting of the Pan American Society for Clinical Virology (PASCV); 2012 April 22-25; Daytona Beach, Florida.
3. Based on actual workflow studies conducted by GenMark scientists at customer sites. Times used are averages across multiple sites for calculations.
SARS-CoV-2 Test
The eSensor SARS-CoV-2 test is a qualitative multiplex assay designed to detect SARS-CoV-2 nucleic acid in nasopharyngeal swabs collected in viral transport media.
This test utilizes the design principles of GenMark’s eSensor Respiratory Viral Panel (RVP), which has been recognized as one of the most sensitive RVP assays available.1 The eSensor SARS-CoV-2 Test consists of PCR amplification and detection reagents test cartridges which are run on the XT-8 System. The eSensor SARS-CoV-2 Test can provide results for 96 samples in 5 hours; laboratories set up for high-throughput, 96-well plate processing of clinical specimens can process 384 specimens per day.
Simple Workflow
This product is distributed according to section IV.C.2 (FDA Notifications) of FDA’s Policy for Coronavirus Disease-2019 Tests During the Public Health Emergency.
1. Popowitch, E.B, O’Neill, S.S., Miller, M.B. Comparison of Four Multiplex Assays for the Detection of Respiratory Viruses: Biofire FilmArray RP, GenMark eSensor RVP, Luminex xTAG RVPv1 and Luminex xTAG RVP FAST. J. Clin. Microbiol. 13 March 2013, doi: 10.1128/JCM.03368-12.
Cystic Fibrosis Genotyping Test
GenMark’s Cystic Fibrosis Genotyping Test uses innovative eSensor® technology to provide patients with accurate genetic carrier screening results.
Comprehensive Testing
- Panel includes the 23 recommended mutations from the American College of Obstetricians and Gynecologists and the American College of Medical Genetics guidelines
Clear, Accurate Results
- Single page report with easy to interpret results
- 100% accuracy and reproducibility in clinical studies
Simple Workflow
- Results in approximately 4 hours including extraction1
- 40 minutes of hands-on time1
For in vitro diagnostic use
1. Based on actual workflow studies conducted by GenMark scientists at customer sites. Times used are averages across multiple sites for calculations.
Thrombophilia Risk Test
GenMark’s Thrombophilia Risk Test uses innovative eSensor® technology to provide a complete picture of inherited risk, aiding in individualized treatment decision-making.
Comprehensive Testing
Detection of all four thrombophilia-related genetic markers:
- Factor II (Prothrombin, FII)
- Factor V (Leiden, FV)
- MTHFR 677 and MTHFR 1298
Flexible Reporting
5 customized report options:
- Full Panel
- FV
- FII
- FV/FII
- MTHFR 677 and 1298
Clear, Accurate Results
- Single-page reports with easy-to-interpret results
- 100% accuracy and reproducibility in clinical trial
Simple Workflow
- Results in approximately 4 hours including extraction1
- 40 minutes of hands-on time1
For in vitro diagnostic use
1. Based on actual workflow studies conducted by GenMark scientists at customer sites. Times used are averages across multiple sites for calculations.
Warfarin Sensitivity Test
GenMark’s Warfarin Sensitivity Test uses innovative eSensor® technology to help identify patients at risk for warfarin-related adverse events.
Comprehensive Testing
- Detection and genotyping of the *2 and *3 alleles of the cytochrome P450 (CYP450) gene and VKORC1 (-1639G>A)
Clear, Accurate Results
- Single-page report with easy-to-interpret results and anticipated level of patient sensitivity
- 100% accuracy and reproducibility in clinical studies
Simple Workflow
- Results in approximately 4 hours including extraction1
- 40 minutes of hands-on time1
For in vitro diagnostic use
1. Based on actual workflow studies conducted by GenMark scientists at customer sites. Times used are averages across multiple sites for calculations.
HCV Direct Test
The HCVg Direct Test is designed to type and subtype Hepatitis C virus (HCV) 1a, 1b, 2, 2a/c, 2b, 3, 4, 5, and 6.
Simple Workflow
For Research Use Only. Not for use in diagnostic procedures.
2C19 Genotyping Test
The 2C19 Genotyping Test is designed for the multiplex detection and genotyping of the *2, *3, *4, *5, *6, *7, *8, *9, *10, *13 and *17 alleles of the cytochrome P450 (CYP450) 2C19 gene.
Simple Workflow
- Results in approximately 4 hours including extraction1
- 40 minutes of hands-on time1
For Research Use Only. Not for use in diagnostic procedures.
1. Based on actual workflow studies conducted by GenMark scientists at customer sites. Times used are averages across multiple sites for calculations.
